Across bioprocessing, pharmaceuticals, enzyme manufacturing and fermentation workflows, maintaining particulate control is essential for product quality and regulatory compliance. As Australian laboratories continue shifting toward single-use technologies and high-efficiency clarification methods, demand for dependable depth filters in Australia has grown significantly.

The Claricap M02 Depth Filter Capsule (23 cm²)—available from CoPure—brings advanced material science, controlled manufacturing and robust performance to small-scale clarification and lab-level filtration tasks.

What Makes the Claricap M02 Different?

The Claricap M02 capsule is engineered using high-purity cellulose fibres, diatomaceous earth, and synthetic resins, combined through a proprietary manufacturing process. This creates a three-dimensional interwoven structure that functions as a true depth filtration medium rather than a simple surface filter.

This internal structure delivers three critical advantages:

Progressive Pore-Size Gradient

As liquid moves through the capsule, the pore size gradually decreases. This allows:

• Early-stage retention of large particles 
• Mid-layer capture of smaller colloids 
• Deep-layer adsorption of fine impurities
  

This multi-layer mechanism increases both filtration efficiency and dirt-holding capacity, reducing the number of filter changes required in lab processes.

High Permeability with Diatomaceous Earth

The inclusion of diatomaceous earth enhances:

• Particle adsorption 
• Flow performance 
• Structural stability
  

The naturally porous silica matrix supports higher throughputs—important when dealing with viscous fermentation broths or biological fluids.

Optimised Wet Strength and Charge Properties

A small proportion of engineered synthetic resin strengthens the structure and imparts a surface charge, enabling electrostatic adsorption of contaminants. This is especially beneficial for:

• Host cell debris 
• Protein aggregates 
• Colloidal impurities
  

Built for High-Purity Applications

The Claricap M02 capsule is validated for modern regulatory expectations, making it ideal for biopharmaceutical and high-purity chemical workflows.

Regulatory & Quality Compliance

• USP <87> and <88> Class VI Biological Safety 
• FDA 21 CFR compliance for indirect food additives 
• Bacterial endotoxin level < 0.25 EU/mL (LAL) 

These certifications underscore its suitability for applications where extractables, endotoxins and contamination risk must be tightly controlled.

Operational Durability

• Max Operating Pressure: 50 psi (3.5 bar) at ≤40°C 
• Forward Differential Pressure: 30 psi (2.1 bar) 
• Reverse Differential Pressure: 15 psi (1.0 bar) 
• Autoclave Resistance: 2 cycles at 123°C for 60 minutes
  

This durability supports lab-scale sterilisation workflows without compromising filter integrity.

A Scalable, Single-Use Filtration Strategy

Modern labs increasingly adopt single-use systems to avoid cross-contamination, reduce cleaning costs and streamline validation. The Claricap M02 capsule aligns with these operational priorities.

Key Advantages

• Linear scale-up design: consistent path length, dead volume and flow characteristics 
• Single-use format: eliminates CIP steps, saving both time and resources 
• Modular architecture: supports processes from 0.5 L to more than 10,000 L 
• High target recovery: minimises product losses during clarification 
• Compatibility: fits Cobetter and other common market holders
  

For pilot facilities and R&D labs that frequently adjust workflows, this flexibility is a practical advantage.

Technical Specifications at a Glance

These compact dimensions make the M02 well-suited for benchtop experiments, small-volume filtration and pre-screening before scale-up.

Where the Claricap M02 Excels

The Claricap M02 capsule supports a broad range of laboratory and bioprocess tasks, including:

Fermentation Broth Clarification

Captures cell debris, insoluble matter and colloidal by-products without clogging early.

Cell Culture Fluid Clarification

Ideal for upstream bioprocess workflows, especially for mammalian and microbial cultures.

Serum and Blood Product Filtration

Low extractables and high retention efficiency make it suitable for sensitive biological fluids.

Enzyme Preparation Filtration

Supports removal of aggregates and insolubles that interfere with enzyme stability.

Traditional Pharmaceutical Filtration

Useful in decolorization, impurity removal and polishing of botanical or complex formulations.

Viscous or Colloidal Liquid Filtration

The gradient structure and diatomaceous earth matrix handle difficult fluids with fewer blockages.

Why Depth Filters Matter for Australia’s Modern Lab Landscape

As Australian laboratories continue to advance in bioprocessing, biotherapeutics, environmental testing and chemical R&D, reliable depth filters in Australia are essential for meeting quality, compliance and workflow efficiency needs.

With rising pressure for sterility assurance, reduced downtime, and scalable single-use solutions, the Claricap M02 offers a balance of:

• High-purity materials 
• Strong contaminant retention 
• Robust mechanical performance 
• Regulatory alignment 

This makes it a dependable choice for labs looking to enhance their filtration strategies without compromising on safety or data integrity.

For Further Enquiry Contact- sales@copure.com.au